Carl Zeiss Introduces Interface for Correlative Light and Electron Microscopy
August 27, 2010 – 2:23 am
Ultra-thin section of the brain of a zebra finch. Fluorescence labeled vesicle in a neuron, overlaid with scanning electron microscope image.
Carl Zeiss has introduced a hardware/software interface to connect light and scanning electron microscopes for correlative microscopy in the life sciences. The “Shuttle & Find” interface enables users to recall regions of interest in fixed specimens in an electron microscope, which were previously identified in a light microscope and vice versa. The entire process takes only a few seconds. This can open up new dimensions in microscopy, enabling rapid and precise overlay of light and electron microscope images, high-resolution magnification of the details and the merger of functional and structural information. Read more…



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